Forensic Context

A study in human skin tissue demonstrated that the mir-6868-3p is upregulated four days post-burn in deep partial thickness burn skin compared to normal skin and is also upregulated in burn hypertrophic scar tissue [Siu et al. DOI:10.1111/wrr.13100]. Separate research in human postmortem brain tissue from individuals with alcohol use disorder found the mir-6868-3p was downregulated in the amygdala, caudate nucleus, cerebellum, prefrontal cortex, and putamen, and this dysregulation was part of identified miRNA-mRNA regulatory networks [Lim et al. DOI:10.1038/s41398-021-01635-w].