Forensic Context

A study in humans demonstrated that recreational alcohol consumption significantly altered serum microRNA profiles, with the mir-6879-3p showing a 3.51-fold increase and effectively distinguishing post-exposure from pre-exposure states with an area under the ROC curve >0.8 [Ten Berg et al. DOI:10.1080/1354750X.2018.1499128]. A subsequent review confirmed mir-6879-3p's diagnostic potential, noting its increased serum levels after alcohol exposure and its inclusion among microRNAs that distinguished post-alcohol states with high discriminatory power [Ferguson et al. DOI:10.3389/Fnmol.2022.1032362].