Basic Information

Symbol
hsa-mir-7-1
RNA class
miRNA miRNA hairpin
Alias
MIR7-1 MicroRNA 7-1 Hsa-MiR-7-1-3p Hsa-Mir-7-1 MIRN7-1 Hsa-Mir-7-P2_pre MIMAT0004553 MIMAT0000252 Hsa-MiR-7-5p MI0000263 MiR-7-5p Mir-7-1 hsa-mir-7a
Location (GRCh38)
9:83969748-83969857
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-7-1
Sequence length
110 nt
GC content
0.4182

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-47.70 kcal/mol
Thermodynamic ensemble
Free energy: -49.45 kcal/mol
Frequency: 0.0581
Diversity: 6.04
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
.((((.((((((((.((.((((((((.(((((.(((((((.(((((((((((....)))))..)))))))))))))))))).)))))))).)))))))).)).))))...
Thermodynamic Ensemble Prediction
.((((.((((((((.((.((((((((.(((((.(((((((((((((((((((....)))))..)))))))))))))))))).)))))))).)))))))).)).))))...
Forensic Context

A review of literature across diverse species including human and mouse indicates that the mir-7-1 is subject to target-directed miRNA degradation (TDMD) mediated by the highly complementary long non-coding RNA Cyrano, leading to its specific downregulation [Shang et al. DOI:10.1038/s41576-023-00611-y].