Basic Information
Symbol
hsa-mir-7-3
RNA class
miRNA
miRNA hairpin
Alias
MIR7-3
MicroRNA 7-3
Hsa-Mir-7-3
MIRN7-3
Hsa-Mir-7-P4_pre
MIMAT0000252
Hsa-MiR-7-5p
MI0000265
MiR-7-5p
Mir-7-3
Location (GRCh38)
19:4770670-4770779
Forensic tag(s)
Individual identification
Other applications
External database
Sequence & Structure
Secondary Structure
Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-38.00 kcal/mol
Thermodynamic ensemble
Free energy:
-40.23 kcal/mol
Frequency:
0.0267
Diversity:
11.12
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
......(((.((....(((((.((((((((.((..(.((.(((((((.((((((.((......)).))))))))))))))).)..)).))))))))))))))).)))...
Thermodynamic Ensemble Prediction
......(((.((....(((((.((((((((.((..(.((.((((((((((((((.{(......}).))))))))))))))).)..)).)))))))))))))))}))}...
Forensic Context
A study in humans demonstrated that the mir-7-3 is significantly downregulated in plasma-derived exosomes from trauma patients compared to elective surgery controls, with this downregulation being particularly pronounced in male patients [Munley et al. DOI:10.1097/TA.0000000000004225]. A study in humans demonstrated that the mir-7-3 is differentially expressed within monozygotic twin pairs, with its expression pattern validated by qRT-PCR assays showing differential expression in 7 out of 18 twin pairs using a 2-fold change criterion and 8 out of 18 pairs using a 1.5-fold change criterion [Xiao et al. DOI:10.1016/j.fsigen.2019.05.003].