Basic Information

Symbol
hsa-mir-711
RNA class
miRNA miRNA hairpin
Alias
MIR711 MicroRNA 711 Hsa-Mir-711 MIMAT0012734 Hsa-MiR-711 MI0012488
Location (GRCh38)
3:48578902-48578977
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Wound age identification Sudden death from CNS diseases
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-711
Sequence length
76 nt
GC content
0.5789

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-35.60 kcal/mol
Thermodynamic ensemble
Free energy: -36.55 kcal/mol
Frequency: 0.3959
Diversity: 1.96
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
.((.((((...(((((((((..((((.((.(((......))).)))))).)))))))))..)))).))........
Thermodynamic Ensemble Prediction
.((.((((.,.(((((((({..((((.((.(((......))).)))))).))))))))).,)))).))........
Forensic Context

A study in mice and humans demonstrated that the mir-711 is significantly upregulated in antemortem burned skin compared to intact and postmortem burned skin, with elevated levels detectable until 120 hours postmortem in mice and 48 hours after autopsy in human cases, and its up-regulation appears related to burn severity [Zhang et al. DOI:10.1080/20961790.2020.1719454]. In a separate study on spinal cord injury, the mir-711 was mentioned as being strongly upregulated in a murine SCI model, where it downregulates Ang-1/Akt signaling [Hörauf et al. DOI:10.3390/ijms262210954].