Forensic Context

A study in humans demonstrated that the mir-758-3p was downregulated (-5.07 fold) in postischemic left ventricular samples following acute myocardial ischemia [Saddic et al. DOI:10.1152/physiolgenomics.00049.2015]. In a separate human study, the mir-758-3p was identified as a differentially expressed microRNA shared across two pairs of monozygotic twins, suggesting its potential role in distinguishing genetically identical individuals in forensic identification [Xiao et al. DOI:10.1016/j.fsigen.2019.05.003].