Basic Information

Symbol
hsa-mir-1296
RNA class
miRNA miRNA hairpin
Alias
MIR1296 MicroRNA 1296 Hsa-MiR-1296-5p Hsa-Mir-1296 MIRN1296 Hsa-Mir-1296_pre Hsa-MiR-1296-3p MIMAT0026637 MIMAT0005794 MI0003780 Mir-1296
Location (GRCh38)
3:184241405-184241489
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis Other applications
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-1296
Sequence length
92 nt
GC content
0.5761

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-50.50 kcal/mol
Thermodynamic ensemble
Free energy: -52.18 kcal/mol
Frequency: 0.0653
Diversity: 11.16
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
.(((((((....(((((((((....(((((((.((((((..((((....))))..)))))))))))))....))))))))))))))))....
Thermodynamic Ensemble Prediction
.{({{(({..,((((((((((.,..(((((((.((((((..((({....))))..)))))))))))))..,.)))))))))))}))))....
Forensic Context

A study in humans demonstrated that the mir-1296 was significantly decreased in plasma-derived exosomes from acute myocardial infarction subjects compared to controls, identifying it as a potential biomarker for postmortem diagnosis [Kim et al. DOI:10.3390/ijms25179619]. In rhesus macaques, the mir-1296 was used as a feature in a four-group survival prediction model at Day 6 and in a pleural effusion prediction model by gender at Day 6 following whole thorax irradiation [May et al. DOI:10.1038/s41598-022-16316-x].