Basic Information

Symbol
hsa-mir-760
RNA class
miRNA miRNA hairpin
Alias
MIR760 MicroRNA 760 Hsa-Mir-760 Hsa-MiR-760 MIRN760 Hsa-Mir-760_pre MIMAT0004957 MI0005567 Mir-760
Location (GRCh38)
X:119646738-119646848
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Wound age identification Sudden cardiac death diagnosis
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-760
Sequence length
80 nt
GC content
0.6375

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-39.50 kcal/mol
Thermodynamic ensemble
Free energy: -41.21 kcal/mol
Frequency: 0.0625
Diversity: 6.94
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
.(((..((((.((((.(((....((((((((.((((.........))))))))))))..))).)))).))))..)))...
Thermodynamic Ensemble Prediction
.(((..((((.((((.(((.,,.(((((((({((((.........))))))))))))}.))).)))).))))..)))...
Forensic Context

A study in humans demonstrated that the mir-760 is downregulated in hypertrophic scar tissue compared to normal tissue [Siu et al. DOI:10.1111/wrr.13100], while a separate investigation in human heart failure patients after acute myocardial infarction found it was upregulated in peripheral blood mononuclear cells from individuals with sacubitril/valsartan resistance compared to non-resistant patients [Su et al. DOI:10.1016/j.ejphar.2023.175547].