Basic Information
Symbol
hsa-miR-760
RNA class
miRNA
mature miRNA
Alias
hsa-miR-760
MIR760
MicroRNA 760
Location (GRCh38)
-
Forensic tag(s)
Sudden cardiac death diagnosis
Other applications
External database
Sequence & Structure
Secondary Structure
Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-39.50 kcal/mol
Thermodynamic ensemble
Free energy:
-41.21 kcal/mol
Frequency:
0.0625
Diversity:
6.94
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
.(((..((((.((((.(((.,,.(((((((({((((.........))))))))))))}.))).)))).))))..)))...
Forensic Context
A study in humans demonstrated that the miR-760 is downregulated in hypertrophic scar tissue compared to normal tissue [Siu et al. DOI:10.1111/wrr.13100], while a separate investigation in human heart failure patients after acute myocardial infarction found it was upregulated in peripheral blood mononuclear cells from individuals with sacubitril/valsartan resistance compared to non-resistant patients [Su et al. DOI:10.1016/j.ejphar.2023.175547].