Basic Information

Symbol
hsa-mir-764
RNA class
miRNA miRNA hairpin
Alias
MIR764 MicroRNA 764 Hsa-Mir-764 MIMAT0010367 Hsa-MiR-764 MI0003944
Location (GRCh38)
22:21652981-21653058
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Drug abuse diagnoses Mechanical injury analysis Wound age identification
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-764
Sequence length
85 nt
GC content
0.5059

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-39.60 kcal/mol
Thermodynamic ensemble
Free energy: -40.99 kcal/mol
Frequency: 0.1050
Diversity: 3.92
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
((((..((.(((((.(((.((((((.((((((((.(((.........))).)))))))).)).))))))).))))).))..))))
Thermodynamic Ensemble Prediction
{(((..((.(((((.(((.((((((.((((((((.(((.,.....,.))).)))))))).)).))))))).))))).))..)))}
Forensic Context

A study in rats demonstrated that the mir-764 is differentially expressed in the brain during cocaine withdrawal, with rno-miR-764-5p being downregulated in the infralimbic prefrontal cortex when comparing 4-week abstinence to 18-hour withdrawal [Kumaresan et al. DOI:10.3390/Biomedicines11051368]. In human skin, hsa-miR-765, a related biomarker, is upregulated in deep partial thickness burn skin four days post-burn and in burn hypertrophic scar tissue compared to normal skin [Siu et al. DOI:10.1111/wrr.13100]. In a separate rat model of oleic acid-induced acute lung injury, the mir-764 was also observed as a potential biomarker, showing a 2.85-fold upregulation at 3 and 6 hours post-challenge [Lee et al. DOI:10.3892/Mmr.2014.2155].