Basic Information

Symbol
hsa-miR-764
RNA class
miRNA mature miRNA
Alias
hsa-miR-764 MIR764 MicroRNA 764
Location (GRCh38)
-
Forensic tag(s)
Drug abuse diagnoses Wound age identification Sudden death from respiratory system disease
External database
miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-miR-764
Sequence length
22 nt
GC content
0.5909

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-39.60 kcal/mol
Thermodynamic ensemble
Free energy: -40.99 kcal/mol
Frequency: 0.1050
Diversity: 3.92
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
((((..((.(((((.(((.((((((.((((((((.(((.........))).)))))))).)).))))))).))))).))..))))
Thermodynamic Ensemble Prediction
{(((..((.(((((.(((.((((((.((((((((.(((.,.....,.))).)))))))).)).))))))).))))).))..)))}
Forensic Context

A study in rats demonstrated that the miR-764 is differentially expressed in the brain during cocaine withdrawal, with rno-miR-764-5p being downregulated in the infralimbic prefrontal cortex when comparing 4-week abstinence to 18-hour withdrawal [Kumaresan et al. DOI:10.3390/Biomedicines11051368]. In human skin, hsa-miR-765, a related biomarker, is upregulated in deep partial thickness burn skin four days post-burn and in burn hypertrophic scar tissue compared to normal skin [Siu et al. DOI:10.1111/wrr.13100]. In a separate rat model of oleic acid-induced acute lung injury, the miR-764 was also observed as a potential biomarker, showing a 2.85-fold upregulation at 3 and 6 hours post-challenge [Lee et al. DOI:10.3892/Mmr.2014.2155].