Basic Information

Symbol
hsa-mir-766
RNA class
miRNA miRNA hairpin
Alias
MIR766 MicroRNA 766 Hsa-MiR-766-5p Hsa-MiR-766-3p Hsa-Mir-766 MIRN766 Hsa-Mir-766_pre MIMAT0003888 MIMAT0022714 MI0003836 Mir-766
Location (GRCh38)
Forensic tag(s)
Other applications

Sequence & Structure

Transcript ID
hsa-mir-766
Sequence length
111 nt
GC content
0.5586

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-49.40 kcal/mol
Thermodynamic ensemble
Free energy: -50.58 kcal/mol
Frequency: 0.1471
Diversity: 8.02
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
((.((((...(((...((((.(((((((..((((...(((.(((((....(((.........)))..))))).)))...)))).))))))).))))....)))..))))))
Thermodynamic Ensemble Prediction
((.((((...(((...((((.(((((((..((((...(((.(((((,,.,(({.....,}..,))..))))).)))...)))).))))))).))))....)))..))))))
Forensic Context

A study in humans demonstrated that the mir-766 is associated with reduced physical function, as higher expression was linked to lower activity of daily living strength scores in older monozygotic twins, with this negative association validated in both individual and twin-pair level cross-sectional analyses [La Grotta et al. DOI:10.1016/j.mad.2025.112099]. A study in older human monozygotic twins identified the mir-766 as a circulating plasma microRNA significantly associated with activity of daily living (ADL) strength scores in cross-sectional analysis, where a negative beta coefficient indicated reduced physical function with higher expression, and this association was validated in both individual and twin-pair level analyses [Rossella La Grotta et al. DOI:10.1016/j.mad.2025.112099].