Forensic Context

A study in humans demonstrated that the mir-766 is associated with reduced physical function, as higher expression was linked to lower activity of daily living strength scores in older monozygotic twins, with this negative association validated in both individual and twin-pair level cross-sectional analyses [La Grotta et al. DOI:10.1016/j.mad.2025.112099]. A study in older human monozygotic twins identified the mir-766 as a circulating plasma microRNA significantly associated with activity of daily living (ADL) strength scores in cross-sectional analysis, where a negative beta coefficient indicated reduced physical function with higher expression, and this association was validated in both individual and twin-pair level analyses [Rossella La Grotta et al. DOI:10.1016/j.mad.2025.112099].