Forensic Context

A review of human studies identified 197 miRNAs associated with wound healing, burn wound healing, and scarring, with the miR-767-5p not being among the specifically listed dysregulated miRNAs in human skin burns, wound healing, or hypertrophic scar tissue [Siu et al. DOI:10.1111/wrr.13100]. A subsequent forensic study established a multi-class support vector machine model for body fluid identification using 12 key miRNA markers, but the miR-767-5p was not included in the evaluated set of 28 promising body fluid-specific markers or the final model [Li et al. DOI:10.1016/j.fsigen.2024.103180]. A systematic review of studies in humans, rats, mice, zebrafish, and macaques synthesized that the miR-767-5p is upregulated in alcoholism and targets genes involved in cellular adhesion, differentiation, and migration [Occhipinti et al. DOI:10.3390/Ijms242317122].