Basic Information

Symbol
hsa-mir-768
RNA class
miRNA miRNA hairpin
Alias
SNORD71 Small Nucleolar RNA, C/D Box 71 Hsa-Mir-768 HBII-239 MicroRNA 768 MIRN768 SnoDB0803 SNORD71 hsa-mir-768
Location (GRCh38)
19:20399272-20399354
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Tissue/body fluid identification Other applications
External database
HGNC NCBI Ensembl miRBase

Sequence & Structure

Transcript ID
hsa-mir-768
Sequence length
86 nt
GC content
0.4884

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-27.70 kcal/mol
Thermodynamic ensemble
Free energy: -28.57 kcal/mol
Frequency: 0.2438
Diversity: 5.16
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context

A study in humans established a multi-class support vector machine classification model for forensic body fluid identification using TaqMan RT-qPCR, which achieved 98% accuracy on an independent test set and demonstrated utility on aged casework samples [Li et al. DOI:10.1016/j.fsigen.2024.103180]. A study in human ovarian cancer samples identified the mir-768-5p as part of a multi-dimensional module (md-module 5) derived from integrative analysis of DNA methylation, gene expression, and microRNA expression data, where it was associated with the TGF-b signaling pathway and its targets included EP300, E2F5, and BMPR1A [Zhang et al. DOI:10.1093/nar/gks725].