Basic Information

Symbol
hsa-mir-769
RNA class
miRNA miRNA hairpin
Alias
MIR769 MicroRNA 769 Hsa-MiR-769-5p Hsa-MiR-769-3p Hsa-Mir-769 MIRN769 Hsa-Mir-769_pre MIMAT0003886 MIMAT0003887 MI0003834 Mir-769
Location (GRCh38)
Forensic tag(s)
Cause of death analysis

Sequence & Structure

Transcript ID
hsa-mir-769
Sequence length
118 nt
GC content
0.6186

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-60.80 kcal/mol
Thermodynamic ensemble
Free energy: -62.64 kcal/mol
Frequency: 0.0507
Diversity: 12.25
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
..(((((.(((((..(((.((((((((.((((((((((.(((.(((.((((.(((........))))))).))).))).)))))))))).)))))))).)))..))..))).))))).
Thermodynamic Ensemble Prediction
..(((((.((({(..(((.((((((((.((((((((((.(((.(((.((((.,((.......,})})))).))).))),)))))))))).)))))))).)))..}}..))).))))).
Forensic Context

A study in rhesus macaques (Macaca mulatta) demonstrated that the mir-769 was identified as one of the ten most statistically significant common radiation response markers in serum following whole thorax irradiation, with expression changes measured via RNA sequencing and validated by qRT-PCR [May et al. DOI:10.1038/s41598-022-16316-x].