Forensic Context

A study in humans demonstrated that the miR-1296-5p was significantly decreased in plasma-derived exosomes from acute myocardial infarction patients compared to controls, identifying it as a potential biomarker for this condition [Kim et al. DOI:10.3390/ijms25179619]. In a separate investigation using a Göttingen minipig model of lethal total body irradiation, the miR-1296-5p was found to be down-regulated in plasma during the Early and Mid post-exposure phases, marking it as an early radiation response marker [Chakraborty et al. DOI:10.1038/s41598-023-45250-9].