Basic Information

Symbol
hsa-mir-802
RNA class
miRNA miRNA hairpin
Alias
MIR802 MicroRNA 802 Hsa-Mir-802 Hsa-MiR-802 MIRN802 Hsa-Mir-459_pre MIMAT0004185 MI0003906
Location (GRCh38)
16:30893903-30893985
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Wound age identification
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-802
Sequence length
94 nt
GC content
0.3723

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-34.80 kcal/mol
Thermodynamic ensemble
Free energy: -36.71 kcal/mol
Frequency: 0.4047
Diversity: 2.97
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
...((((((.(((((.(.(((.((((((((((.(((((((............))))))))))))))))).))).).))))).))))))......
Thermodynamic Ensemble Prediction
{{{(,((((,(((((.(.(((.((((((((((.((((((({{.......)}.))))))))))))))))).))).).))))).,)))))}.}}}}
Forensic Context

A review of human studies identified 197 miRNAs associated with wound healing, burn wound healing, and scarring, with specific dysregulation patterns observed in human skin tissue and cell lines post-thermal injury [Siu et al. DOI:10.1111/wrr.13100]. A study in mice demonstrated that the mir-802 is a predictive biomarker for survival, where high levels at day 2 were associated with reduced survival in C57Bl/6 mice and it was associated with TGF-β/SMAD signaling [Rogers et al. DOI: 10.1371/journal.pone.0232411]. In non-human primates, the mir-802 was used as a feature in a survival prediction model at Day 6, contributing to the forecasting of mortality following thoracic irradiation [May et al. DOI: 10.1038/s41598-022-16316-x].