Basic Information

Symbol
hsa-miR-877-3p
RNA class
miRNA mature miRNA
Alias
hsa-miR-877 MIR877 MicroRNA 877
Location (GRCh38)
-
Forensic tag(s)
Mechanical injury analysis Sudden cardiac death diagnosis
External database
miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-miR-877-3p
Sequence length
21 nt
GC content
0.6190
Forensic Context

A study in mice demonstrated that the mir-877 was down-regulated -2.78-fold in the hippocampus after traumatic brain injury at normal temperature and -2.33-fold under low-temperature conditions at 4 hours post-injury [Wang et al. DOI:10.1258/ebm.2012.012123]. A study in rats identified the mir-877 as a key biomarker of acute myocardial ischemia (AMI) via LASSO regression, with a diagnostic area under the curve (AUC) of 75% [Zhao et al. DOI:10.3390/cimb47110889].