Forensic Context

A study in humans demonstrated that miR-885-3p was significantly downregulated in plasma at 48 hours post-injury in patients with acute spinal cord injury compared to healthy controls, as identified via next-generation sequencing [Hörauf et al. DOI:10.3390/ijms262210954]. A study in mice demonstrated that the miR-885-3p could distinguish plasma from unirradiated and irradiated head and neck squamous cell carcinoma patients [Jia et al. DOI:10.3389/fcell.2022.861451], while research in human monozygotic twins identified the miR-885-3p as differentially expressed and shared across three pairs, indicating its potential for forensic individualization [Xiao et al. DOI:10.1016/j.fsigen.2019.05.003].