Forensic Context

A study in humans demonstrated that the miR-885-5p was downregulated in plasma at 48 hours post-injury in spinal cord injury patients compared to healthy controls using next-generation sequencing, though droplet digital PCR validation did not show a significant difference [Hörauf et al. DOI:10.3390/ijms262210954]. In a separate human study, the miR-885-5p was identified as differentially expressed and shared across two pairs of monozygotic twins in blood samples analyzed via miRNA microarray, suggesting its potential role in distinguishing genetically identical individuals [Xiao et al. DOI:10.1016/j.fsigen.2019.05.003].