Basic Information

Symbol
hsa-mir-886
RNA class
miRNA miRNA hairpin
Alias
VTRNA2-1 VaulU RNA 2-1 Hsa-Mir-886 Pre-MiR-886 VtRNA2 Hvg-5 CBL-3 Nc886 MicroRNA 886 MIRN886 MIR886 Cord Blood LymphocyUe-Derived Noncoding RNA 3 Noncoding RNA 886 Vault RNA 2 SvtRNA2-1a CBL3 hsa-mir-886
Location (GRCh38)
5:136080470-136080597
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Wound age identification Forensic psychiatry evaluation
External database
HGNC NCBI Ensembl OMIM miRBase

Sequence & Structure

Transcript ID
hsa-mir-886
Sequence length
108 nt
GC content
0.5556

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-34.20 kcal/mol
Thermodynamic ensemble
Free energy: -36.64 kcal/mol
Frequency: 0.0190
Diversity: 17.15
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
.(((((((....(((.(..((((((....(((((.(((((((.........))))......).))))))).....)).))))..).)))..)))))))..........
Thermodynamic Ensemble Prediction
.(((((((....(((.(..((((((....(((((.(((((({.........)}}}...,,,).))))))).....)),))))..).)))..)))))))..........
Forensic Context

A review of human studies identified 197 miRNAs associated with wound healing, burn wound healing, and scarring, with specific expression patterns in human skin tissue and cells post-burn and in hypertrophic scars [Siu et al. DOI:10.1111/wrr.13100]. A study in humans demonstrated that the mir-886-3p was upregulated by >40% in bipolar disorder subjects compared to non-psychiatric controls, though this change was not statistically significant (p=0.28) in postmortem prefrontal cortex tissue [Smalheiser et al. DOI:10.1371/journal.pone.0086469].