Basic Information

Symbol
hsa-mir-1299
RNA class
miRNA miRNA hairpin
Alias
MIR1299 MicroRNA 1299 Hsa-Mir-1299 Hsa-MiR-1299 MIRN1299 MIMAT0005887 MI0006359
Location (GRCh38)
9:40929010-40929092
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-1299
Sequence length
83 nt
GC content
0.5060

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-34.10 kcal/mol
Thermodynamic ensemble
Free energy: -35.28 kcal/mol
Frequency: 0.1483
Diversity: 3.50
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
(((((..((((.((((((((((.(((((((.((..............)))))))))....)))))))))).)))).)))))..
Thermodynamic Ensemble Prediction
((((({.{(((.((((((((((.(((((((.((..............)))))))))....)))))))))).))))})))))..
Forensic Context

A study in humans identified hsa-miR-1299 as a significantly increased circulating miRNA in the plasma of acute myocardial infarction (MI) patients compared to healthy controls using next-generation sequencing [Baulina et al. DOI:10.1016/j.yjmcc.2018.07.129]. Another human study found hsa-miR-1299 to be the most up-regulated differentially expressed miRNA in myocardial fibrosis after acute myocardial infarction, as determined by RNA sequencing [Wang et al. DOI:10.2147/IJGM.S329391]. In a separate human study of coronary artery disease patients, the mir-1299 was also found to be upregulated in the whole blood of those with recurrent MI after percutaneous coronary intervention, with differential expression remaining significant after false-discovery rate correction [Onuoha et al. DOI:10.1111/cts.13307].