Forensic Context

A study in human samples demonstrated that hsa-miR-9-5p exhibited considerably higher expression in pooled brain tissue, identifying it as a promising miRNA marker for the forensic identification of brain tissue [Sauer et al. DOI:10.1016/j.fsigen.2017.02.002]. A study in mice demonstrated that the miR-9-5p is upregulated following traumatic brain injury and contributes to neurological recovery by attenuating brain microvascular damage and neuroinflammation through activation of the Hedgehog pathway and inhibition of NF-κB/MMP-9 [Li et al. DOI:10.1016/j.neuint.2023.105643].