Basic Information

Symbol
hsa-mir-92a-1
RNA class
miRNA miRNA hairpin
Alias
MIR92A1 MicroRNA 92a-1 Hsa-MiR-92a-1-5p Hsa-MiR-92a-3p Hsa-Mir-92a-1 Hsa-Mir-92-1 MicroRNA 92-1 MIRN92-1 MIRN92A1 Putative MicroRNA 17 Host Gene Protein Putative MicroRNA Host Gene 1 Protein Hsa-Mir-92-P1a_pre MIMAT0004507 MIMAT0000092 MIRN92A-1 MiRNA92-1 Mir-92a-1 MI0000093 C13orf25 MIR17HG MIR92-1 MIRHG1 MIRH1 hsa-mir-92-1 hsa-mir-92a
Location (GRCh38)
13:91351314-91351391
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Mechanical injury analysis
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-92a-1
Sequence length
78 nt
GC content
0.4872

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-35.50 kcal/mol
Thermodynamic ensemble
Free energy: -37.43 kcal/mol
Frequency: 0.0433
Diversity: 5.99
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
....({..((((((((((((.((,{(((((((((((......)))))))))))))).)))))))))))).})).....
Forensic Context

A study in human plasma demonstrated that hsa-miR-92a-3p was upregulated within the first 24 hours after traumatic brain injury (TBI) [Qin et al. DOI:10.1371/journal.pone.0204051], while another study in human formalin-fixed paraffin-embedded brain tissue utilized hsa-miR-92a-3p as a stable housekeeping gene for normalization in the geometric mean with hsa-miR-16-5p during the relative quantification of diagnostic miRNAs in fatal TBI cases [Bonin et al. DOI:10.3390/ijms241310836]. Another investigation in rats, mice, and rabbits reported that inhibition of miR-92a, delivered via a PEI-DA copolymer system, promotes angiogenesis and wound closure in burn injury models, with this inhibitor advancing to clinical trials for wound healing [Badanina et al. DOI:10.3390/ijms262010060].