Basic Information

Symbol
hsa-mir-92a-2
RNA class
miRNA miRNA hairpin
Alias
MIR92A2 MicroRNA 92a-2 Hsa-MiR-92a-2-5p Hsa-MiR-92a-3p Hsa-Mir-92a-2 Hsa-Mir-92-2 MicroRNA 92-2 MIRN92-2 MIRN92A2 Hsa-Mir-92-P1c_pre MIMAT0000092 MIMAT0004508 MIRN92A-2 Mir-92a-2 MI0000094
Location (GRCh38)
X:134169538-134169612
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Mechanical injury analysis
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-92a-2
Sequence length
75 nt
GC content
0.4533

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-29.80 kcal/mol
Thermodynamic ensemble
Free energy: -32.19 kcal/mol
Frequency: 0.0207
Diversity: 7.51
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
((.(((.(((((.(((((..((.(((.(((((((((...)))).))))).)))))..))))).))))).))).))
Thermodynamic Ensemble Prediction
,(.(((.{((((.(((((..(,{(((.(((((((((...})))}))))).)))))..))))).))))).))).),
Forensic Context

A study in human plasma demonstrated that hsa-miR-92a-3p was upregulated within the first 24 hours after traumatic brain injury (TBI) [Qin et al. DOI:10.1371/journal.pone.0204051], while another study in human formalin-fixed paraffin-embedded brain tissue utilized hsa-miR-92a-3p as a stable housekeeping gene for normalization in the geometric mean with hsa-miR-16-5p during the relative quantification of diagnostic miRNAs in fatal TBI cases [Bonin et al. DOI:10.3390/ijms241310836]. Another investigation in rats, mice, and rabbits reported that inhibition of miR-92a, delivered via a PEI-DA copolymer system, promotes angiogenesis and wound closure in burn injury models, with this inhibitor advancing to clinical trials for wound healing [Badanina et al. DOI:10.3390/ijms262010060].