Basic Information

Symbol
hsa-mir-92b
RNA class
miRNA miRNA hairpin
Alias
MIR92B MicroRNA 92b Hsa-MiR-92b-5p Hsa-MiR-92b-3p Hsa-Mir-92b MIRN92B Hsa-Mir-92-P1d_pre MIMAT0003218 MIMAT0004792 MI0003560 Mir-92b
Location (GRCh38)
1:155195177-155195272
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Chronological age estimation Postmortem interval inference
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-92b
Sequence length
96 nt
GC content
0.7500

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-66.00 kcal/mol
Thermodynamic ensemble
Free energy: -66.52 kcal/mol
Frequency: 0.4311
Diversity: 4.52
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context

A study in the blow fly Cochliomyia macellaria demonstrated that the mir-92b is a stable marker of intrapuparial developmental age, with qPCR validation confirming its higher expression in earlier intrapuparial and larval stages [Hjelmen et al. DOI:10.3390/insects13100948]. A systematic review of postmortem interval estimation in humans, mice, rats, and pigs identified rno-miR-92b-5p as being significantly upregulated in rat skeletal muscle within 24 hours postmortem [Cianci et al. DOI:10.3390/ijms25158185]. In Sarcophaga peregrina, research established the mir-92b as a robust temporal biomarker for pupal age estimation, where its expression exhibited a marked decline during the first 4–6 days before stabilizing, and polynomial regression models using its expression achieved a high coefficient of determination [Xia et al. DOI:10.3390/insects16080754].