Forensic Context

A study in rats demonstrated that the miR-92b-5p was the most significantly upregulated miRNA in skeletal muscle at 24 hours postmortem, with a fold change of 241.18 [Guardado-Estrada et al. DOI:10.7717/peerj.15409]. A systematic review of human, mouse, rat, and pig studies confirmed that miRNA degradation patterns, including those of the miR-92b-5p, correlate with the postmortem interval and are particularly useful for estimation within short time frames of hours to days [Cianci et al. DOI:10.3390/ijms25158185].