Basic Information

Symbol
hsa-miR-1299
RNA class
miRNA mature miRNA
Alias
hsa-miR-1299 MIR1299 MicroRNA 1299
Location (GRCh38)
-
Forensic tag(s)
Sudden cardiac death diagnosis
External database
miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-miR-1299
Sequence length
22 nt
GC content
0.4545

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-34.10 kcal/mol
Thermodynamic ensemble
Free energy: -35.28 kcal/mol
Frequency: 0.1483
Diversity: 3.50
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
((((({.{(((.((((((((((.(((((((.((..............)))))))))....)))))))))).))))})))))..
Forensic Context

A study in humans identified hsa-miR-1299 as a significantly increased circulating miRNA in the plasma of acute myocardial infarction (MI) patients compared to healthy controls using next-generation sequencing [Baulina et al. DOI:10.1016/j.yjmcc.2018.07.129]. Another human study found hsa-miR-1299 to be the most up-regulated differentially expressed miRNA in myocardial fibrosis after acute myocardial infarction, as determined by RNA sequencing [Wang et al. DOI:10.2147/IJGM.S329391]. In a separate human study of coronary artery disease patients, the miR-1299 was also found to be upregulated in the whole blood of those with recurrent MI after percutaneous coronary intervention, with differential expression remaining significant after false-discovery rate correction [Onuoha et al. DOI:10.1111/cts.13307].