Basic Information

Symbol
hsa-mir-935
RNA class
miRNA miRNA hairpin
Alias
MIR935 MicroRNA 935 Hsa-Mir-935 Hsa-MiR-935 MIRN935 Hsa-Mir-935-V1_pre Hsa-Mir-935-V2_pre MIMAT0004978 MI0005757 Mir-935
Location (GRCh38)
19:53982307-53982397
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-935
Sequence length
91 nt
GC content
0.7912

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-61.20 kcal/mol
Thermodynamic ensemble
Free energy: -62.17 kcal/mol
Frequency: 0.2068
Diversity: 3.15
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context

A study in humans demonstrated that plasma-derived exosomes from severe trauma patients exhibited significant downregulation of the mir-935 compared to operative controls, and this downregulation was specifically linked to pathways involved in hematopoiesis and immune function regulation, such as macrophage polarization [Munley et al. DOI:10.1097/TA.0000000000004225]. A systematic review of animal and human studies found that the mir-935 was upregulated in the testes of diabetic rats and in the serum of type 2 diabetic humans, where it was associated with Leydig cell apoptosis, reduced testosterone, and diabetes-induced testicular damage and steroidogenesis destruction [Latifi et al. DOI:10.1007/s11033-024-10197-1].