Basic Information

Symbol
hsa-mir-940
RNA class
miRNA miRNA hairpin
Alias
MIR940 MicroRNA 940 Hsa-Mir-940 Hsa-MiR-940 MIRN940 MIMAT0004983 MI0005762 Mir-940
Location (GRCh38)
16:2271747-2271840
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Tissue/body fluid identification Mechanical injury analysis
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-940
Sequence length
94 nt
GC content
0.7660

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-52.90 kcal/mol
Thermodynamic ensemble
Free energy: -55.07 kcal/mol
Frequency: 0.2522
Diversity: 6.55
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
(((.(((.,((((((((.....((((((((((((.(.(..((((.,.......))..))..).).))))))))))))))))))))),))).)))
Forensic Context

A study in humans demonstrated that the mir-940 was downregulated in plasma from patients with mild, moderate, and severe traumatic brain injury compared to healthy controls, as identified by microarray analysis [Qin et al. DOI:10.1371/journal.pone.0204051]. A separate review noted that the mir-940 was found to be upregulated in female plasma and considered a gender-specific biomarker, which is a factor that could influence its reliability for forensic body fluid identification [Silva et al. DOI:10.1016/J.Fsigen.2014.09.002]. A study in humans demonstrated that the mir-940 was used as a housekeeping-gene-like normalizer for miRNA expression across body fluids to create ΔCt values, which was a critical step in developing a logistic regression model for menstrual blood identification [Hanson et al. DOI:10.1002/elps.201400171].