Basic Information

Symbol
hsa-miR-940
RNA class
miRNA mature miRNA
Alias
hsa-miR-940 MIR940 MicroRNA 940
Location (GRCh38)
-
Forensic tag(s)
Mechanical injury analysis Tissue/body fluid identification
External database
miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-miR-940
Sequence length
21 nt
GC content
0.8095

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-52.90 kcal/mol
Thermodynamic ensemble
Free energy: -55.07 kcal/mol
Frequency: 0.2522
Diversity: 6.55
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context

A study in humans demonstrated that the miR-940 was downregulated in plasma from patients with mild, moderate, and severe traumatic brain injury compared to healthy controls, as identified by microarray analysis [Qin et al. DOI:10.1371/journal.pone.0204051]. A separate review noted that the miR-940 was found to be upregulated in female plasma and considered a gender-specific biomarker, which is a factor that could influence its reliability for forensic body fluid identification [Silva et al. DOI:10.1016/J.Fsigen.2014.09.002]. A study in humans demonstrated that the miR-940 was used as a housekeeping-gene-like normalizer for miRNA expression across body fluids to create ΔCt values, which was a critical step in developing a logistic regression model for menstrual blood identification [Hanson et al. DOI:10.1002/elps.201400171].