A study in humans identified plasma extracellular vesicle microRNAs as biomarkers for sudden cardiac death prediction in acute coronary syndrome, with miR-208b-3p and miR-143-3p showing significant upregulation, positive correlation with myoglobin, and fair predictive power (AUC 0.7756 and 0.7778) [Huang et al. DOI:10.1039/D2MO00257D].