Basic Information

Symbol
hsa-mir-95
RNA class
miRNA miRNA hairpin
Alias
MIR95 MicroRNA 95 Hsa-Mir-95 Hsa-MiR-95-3p MIRN95 Hsa-Mir-95-P1_pre Hsa-MiR-95-5p MIMAT0026473 MIMAT0000094 MI0000097 MiR-95
Location (GRCh38)
19:13836440-13836517
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Mechanical injury analysis
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-95
Sequence length
81 nt
GC content
0.4074

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-36.40 kcal/mol
Thermodynamic ensemble
Free energy: -37.27 kcal/mol
Frequency: 0.2421
Diversity: 6.42
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
.(((.((((((..((((((((((((((((((((({({......})}.)))))))))))))))))))))..)))))).))).
Forensic Context

A study in humans demonstrated that the mir-95 is markedly upregulated in trauma plasma and contains pro-inflammatory nucleotide motifs, forming part of a 12-miRNA panel that distinguished trauma from healthy controls with a cross-validated AUROC of 0.98 [Ren et al. DOI:10.1016/j.isci.2025.113569]. This panel, which includes the mir-95, showed strong diagnostic and predictive abilities for overall trauma severity, organ injury, coagulation, endothelial activation, and inflammation, with specific high AUROC values for predicting injury markers like S100B and IL-6.