Forensic Context

A study in humans established a multi-class support vector machine classification model for forensic body fluid identification using TaqMan RT-qPCR, which achieved 98% accuracy on an independent test set [Li et al. DOI:10.1016/j.fsigen.2024.103180]. A study in mice demonstrated that the miR-96-5p is a predictive biomarker for survival, identified in survival analysis of C57Bl/6 mice and associated with TGF-β/SMAD signaling [Rogers et al. DOI:10.1371/journal.pone.0232411]. In human studies, the miR-96-5p was found to be differentially expressed, shared across two pairs of monozygotic twins, indicating its potential role in distinguishing genetically identical individuals [Xiao et al. DOI:10.1016/j.fsigen.2019.05.003].