A review of human studies found that the mir-99a is downregulated 24 hours post-injury in skin wounds compared to unwounded skin [Siu et al. DOI:10.1111/wrr.13100]. A study in rats demonstrated that the mir-99a was significantly upregulated in myocardial tissues following a 15% third-degree burn injury and was validated as a potential biomarker for myocardial damage via qRT-PCR [Guo et al. DOI:10.1080/09168451.2020.1807901].