Basic Information

Symbol
hsa-mir-1-1
RNA class
miRNA miRNA hairpin
Alias
MIR1-1 MicroRNA 1-1 Hsa-MiR-1-3p Hsa-Mir-1-1 MIRN1-1 Hsa-Mir-1-P3_pre MIMAT0031892 MIMAT0000416 Hsa-MiR-1-5p MI0000651 MiRNA1-1 Mir-1-1
Location (GRCh38)
20:62554306-62554376
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Cause of death analysis Sudden cardiac death diagnosis
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-1-1
Sequence length
71 nt
GC content
0.3662

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-29.10 kcal/mol
Thermodynamic ensemble
Free energy: -30.05 kcal/mol
Frequency: 0.2127
Diversity: 4.59
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
(((((.((((((((((((((((..((((((((.....)))...))))).)))))))))))))))).)))))
Thermodynamic Ensemble Prediction
{((((.((((((((((((((((..((((({({.....},,..,))))).)))))))))))))))).))))}
Forensic Context

A study in rats demonstrated that the mir-1-1 was significantly downregulated in skeletal muscle following burn trauma, indicating its potential role in muscle wasting [Zhang et al. DOI:10.5505/tjtes.2015.80707]. In human myocardial infarction, the mir-1-1 was also found to be downregulated in infarcted heart tissue compared to healthy adult hearts [Boštjančič et al. DOI:10.1159/000268088].