Basic Information

Symbol
hsa-mir-1306
RNA class
miRNA miRNA hairpin
Alias
MIR1306 MicroRNA 1306 Hsa-MiR-1306-5p Hsa-MiR-1306-3p Hsa-Mir-1306 MIRN1306 Hsa-Mir-1306_pre MIMAT0005950 MIMAT0022726 MI0006443 Mir-1306
Location (GRCh38)
22:20086058-20086142
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-1306
Sequence length
85 nt
GC content
0.5882

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-30.70 kcal/mol
Thermodynamic ensemble
Free energy: -32.61 kcal/mol
Frequency: 0.0451
Diversity: 9.47
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
.((.((.((((.(((((((......((.((((((((.((.(.....).)).)))))))).))...)))))))..)))).)).)).
Thermodynamic Ensemble Prediction
..(.((.((((.(((((((......((.{(((((((.,{.(.....}.)}.)))))))}.))...)))))))..)))).)).}..
Forensic Context

A systematic review of studies in rats, mice, and humans identified aberrant expression profiles of 25 microRNAs, including the mir-1306, in diabetes associated with male reproductive complications [Latifi et al. DOI:10.1007/s11033-024-10197-1]. Furthermore, a separate review notes the mir-1306 hairpin is located within the DGCR8 coding sequence and is cleaved by Drosha to suppress DGCR8 expression, illustrating a mechanism of autoregulation in microRNA biogenesis [Shang et al. DOI:10.1038/s41576-023-00611-y].