Basic Information

Symbol
hsa-mir-133a-2
RNA class
miRNA miRNA hairpin
Alias
MIR133A2 MicroRNA 133a-2 Hsa-Mir-133a-2 Hsa-MiR-133a-5p Hsa-MiR-133a-3p MIRN133A2 Hsa-Mir-133-P3-V1_pre Hsa-Mir-133-P3-V2_pre MIMAT0026478 MIMAT0000427 Mir-133a-2 MI0000451 hsa-mir-133a
Location (GRCh38)
20:62564912-62565013
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden unexpected death diagnosis Postmortem interval inference
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-133a-2
Sequence length
102 nt
GC content
0.5098

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-47.80 kcal/mol
Thermodynamic ensemble
Free energy: -49.00 kcal/mol
Frequency: 0.1423
Diversity: 5.28
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
.((.(((((((((...((((.(((((((..((.((.((((((((.(........).)))))))).)).))..))))))).))))...)))))..)))).)).
Thermodynamic Ensemble Prediction
.((.(((((((((...((((.(((((((..{{.((.((((((((.{........}.)))))))).)).}}..))))))).))))...)))))..)))).)).
Forensic Context

A study in human heart tissue from sudden infant death syndrome (SIDS) cases demonstrated that the expression of the mir-133a did not differ significantly between SIDS patients and control cases [Courts et al. DOI:10.1016/j.forsciint.2013.02.032]. A systematic review of human, mouse, rat, and pig tissues indicates that microRNA-133a (miR-133a) demonstrates high stability in myocardium, establishing its potential as a reference control marker for postmortem interval estimation in heart tissue [Cianci et al. DOI:10.3390/ijms25158185].