Basic Information

Symbol
hsa-miR-137-5p
RNA class
miRNA mature miRNA
Alias
hsa-miR-137 MIR137 MicroRNA 137
Location (GRCh38)
-
Forensic tag(s)
Mechanical injury analysis Wound age identification Forensic psychiatry evaluation
External database
miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-miR-137-5p
Sequence length
23 nt
GC content
0.4348
Forensic Context

A study in mice demonstrated that the mir-137 is significantly down-regulated in the traumatized cortex during secondary contusion expansion following controlled cortical impact-induced traumatic brain injury, as validated by qRT-PCR [Meissner et al. DOI:10.1089/neu.2015.4077]. The review literature notes that the mir-137 is a therapeutic target in schizophrenia, where it targets genes including NRG2/3, SYN2/3, ATXN1, ERBB4, GSK3B, FZD3, and PTGS2 [Das et al. DOI:10.1080/21655979.2021.2003667].