Basic Information

Symbol
hsa-mir-143
RNA class
miRNA miRNA hairpin
Alias
MIR143 MicroRNA 143 Hsa-MiR-143-5p Hsa-MiR-143-3p Hsa-Mir-143 MIRN143 Hsa-Mir-143_pre MIMAT0000435 MIMAT0004599 MI0000459 Mir-143
Location (GRCh38)
5:149428918-149429023
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Cause of death analysis
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-143
Sequence length
106 nt
GC content
0.5755

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-51.80 kcal/mol
Thermodynamic ensemble
Free energy: -53.32 kcal/mol
Frequency: 0.0847
Diversity: 6.70
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
((((((.((....((((.(..((((((.(((((((((.((((((.((((......)).)).)))))).))))))))).))))))..).))))....)).)))).))
Thermodynamic Ensemble Prediction
((((((.((....((((.(..((((((.(((((((((.((((((.({((......)).}}.)))))).))))))))).))))))..).))))....)).)))).))
Forensic Context

A study in human myocardial autopsy specimens from septic patients identified 32 differentially expressed miRNAs, with hsa-miR-451a showing the largest decrease and hsa-miR-146b-5p the highest fold increase [Pasi Lehto et al. DOI:10.1038/s41598-024-81114-6].