Basic Information

Symbol
hsa-mir-15b
RNA class
miRNA miRNA hairpin
Alias
MIR15B MicroRNA 15b Hsa-MiR-15b-5p Hsa-MiR-15b-3p Hsa-Mir-15b MIRN15B Hsa-Mir-15-P1b_pre MIMAT0000417 MIMAT0004586 MI0000438 MiR-15b
Location (GRCh38)
14:65471102-65471186
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-15b
Sequence length
98 nt
GC content
0.3673

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-29.30 kcal/mol
Thermodynamic ensemble
Free energy: -30.56 kcal/mol
Frequency: 0.1292
Diversity: 4.61
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
.((((.(((((((...(((.(((((((.((.(((((((.(((.((.......))))).))))))).)).))))))).)))...)))))))...)))).
Thermodynamic Ensemble Prediction
.((((.(((((((...(((.(((((((.((.(((((((.(((.{{.......}}))).))))))).)).))))))).)))...)))))))...)))).
Forensic Context

A study in severely injured human patients identified 69 differentially expressed microRNAs, with the mir-15b showing an indirect correlation with TLR3 gene expression [Uhlich et al. DOI:10.1016/j.surg.2014.06.017]. In a separate investigation of young human patients with acute coronary syndrome, the mir-15b was mentioned as being down-regulated in statin-treated unstable angina patients [Tong et al. DOI:10.3390/ijms19051467].