Basic Information

Symbol
hsa-miR-15b-3p
RNA class
miRNA mature miRNA
Alias
hsa-miR-15b MIR15B MicroRNA 15b
Location (GRCh38)
-
Forensic tag(s)
Sudden cardiac death diagnosis Other applications
External database
miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-miR-15b-3p
Sequence length
22 nt
GC content
0.3636
Forensic Context

A study in humans identified the miR-15b-3p as significantly upregulated in the plasma of patients with coronary artery disease compared to normal coronary artery controls, ranking it among the top ten upregulated microRNAs [Zhong et al. DOI:10.1002/jcla.23020]. In non-human primates subjected to whole-thorax lung irradiation, expression of the miR-15b-3p at or below the median abundance at day 15 post-irradiation was associated with statistically significant reduced survival [Rogers et al. DOI:10.1667/RADE-20-00031.1].