Basic Information

Symbol
hsa-mir-151a
RNA class
miRNA miRNA hairpin
Alias
MIR151A MicroRNA 151a Hsa-MiR-151a-3p Hsa-MiR-151a-5p Hsa-Mir-151 MicroRNA 151 MIRN151 MIR151 Hsa-Mir-28-P2_pre Hsa-Mir-151a MIMAT0000757 MIMAT0004697 MI0000809
Location (GRCh38)
16:16300159-16300242
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Individual identification Other applications
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-151a
Sequence length
90 nt
GC content
0.5222

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-45.90 kcal/mol
Thermodynamic ensemble
Free energy: -46.71 kcal/mol
Frequency: 0.2674
Diversity: 3.59
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
.((((((.((((((((((((..((((((((((.(........).)))))))))).)))))))))))).)))))).(((.......)))..
Thermodynamic Ensemble Prediction
.((((((.((((((((((((..((((((((((.(........}.)))))))))).)))))))))))).)))))).(((.......)))..
Forensic Context

A study in human infants demonstrated that the mir-151a was significantly more abundant in breast milk and the gastric content of breast-fed infants compared to formula-fed infants and adult gastric juice, identifying it as a potential biomarker for estimating the last feeding type in forensic casework [Kakimoto et al. DOI:10.1007/S00414-019-02226-7]. Separately, research in human monozygotic twins showed that the mir-151a was differentially expressed between co-twins in peripheral blood, supporting its potential as a molecular marker for discriminating between individuals with identical genomic DNA [Fang et al. DOI:10.1016/j.fsigen.2018.09.011].