Basic Information

Symbol
hsa-mir-151b
RNA class
miRNA miRNA hairpin
Alias
MIR151B MicroRNA 151b Hsa-Mir-151b Hsa-MiR-151b MIMAT0010214 MI0003772
Location (GRCh38)
2:11836933-11836986
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Drug abuse diagnoses Individual identification
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-151b
Sequence length
96 nt
GC content
0.5417

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-29.90 kcal/mol
Thermodynamic ensemble
Free energy: -30.93 kcal/mol
Frequency: 0.4535
Diversity: 3.26
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
..(((((...(((..((((.......(((((((((((...(((..........)))..)))).))))))).......))))..)))....))))).
Thermodynamic Ensemble Prediction
,{(,(((...(((..((((...,...(((((((((((...(((..........)))..)))).)))))))..,,...))))..)))....))))),
Forensic Context

A study in human embryonic stem cell-derived cortical interneurons demonstrated that the mir-151b was upregulated following ethanol exposure, identifying it as part of an alcohol-influenced miRNA-mRNA regulatory network [Lim et al. DOI:10.1038/s41398-021-01635-w]. Separately, an analysis of human blood samples from monozygotic twins identified the mir-151b as differentially expressed and shared across three pairs of twins, suggesting its potential utility as a biomarker for distinguishing genetically identical individuals in forensic identification [Xiao et al. DOI:10.1016/j.fsigen.2019.05.003].