Basic Information

Symbol
hsa-mir-100
RNA class
miRNA miRNA hairpin
Alias
MIR100 MicroRNA 100 Hsa-MiR-100-5p Hsa-MiR-100-3p Hsa-Mir-100 MIRN100 Hsa-Mir-10-P2d_pre MIMAT0004512 MIMAT0000098 MI0000102 MiR-100
Location (GRCh38)
X:77005404-77005501
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-100
Sequence length
80 nt
GC content
0.4625

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-25.70 kcal/mol
Thermodynamic ensemble
Free energy: -26.81 kcal/mol
Frequency: 0.1654
Diversity: 3.87
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
((((....((((.(((.((((((.(((.((((((...........)))))).))).)))))).))).)))).....))))
Thermodynamic Ensemble Prediction
((((..{.((((.(((.((((((.(((.((((((,..........)))))).))).)))))).))).)))).,...))))
Forensic Context

A study in human endothelial cells demonstrated that the mir-100 was repressed at 72 hours post-radiation following 8 Gy and 10 Gy X-ray exposure, with its target mRNAs SOCS2 and CYTL1 being induced, indicating its mechanistic role in the radiation response [Chopra et al. DOI:10.1038/s41598-022-24051-6]. In human skin, the mir-100 was downregulated 24 hours post-injury in skin wounds versus unwounded skin and was also downregulated post-burn in heat-shocked fibroblasts [Siu et al. DOI:10.1111/wrr.13100]. A study in humans and mice demonstrated that the mir-100 promotes STAT3-mediated proliferation of spermatogonial stem cells [Doghish et al. DOI:10.1007/s00210-024-03594-7].