Forensic Context

A study in humans demonstrated that plasma extracellular vesicles containing the miR-152-3p were significantly upregulated in patients with acute coronary syndrome experiencing sudden cardiac death compared to healthy controls [Huang et al. DOI:10.1039/D2MO00257D]. Another human study investigating plaque rupture in ST-segment elevation myocardial infarction patients selected the miR-152-3p from RNA-seq data for further validation as a potential biomarker, though the specific validation outcome for distinguishing plaque phenotypes was not detailed in the provided text [Li et al. DOI:10.1016/j.ygeno.2020.11.019].