Forensic Context

A study in human aortic endothelial cells demonstrated that the miR-100-3p was repressed at 72 hours post-irradiation with 8 Gy and 10 Gy X-rays, with its target mRNAs SOCS2 and CYTL1 being induced, indicating its mechanistic role in the dose- and time-dependent radiation response [Chopra et al. DOI:10.1038/s41598-022-24051-6]. A review of human skin burn and wound healing literature reported that hsa-miR-100 was downregulated 24 hours post-injury in skin wounds and was also downregulated in heat-shocked fibroblasts post-burn [Siu et al. DOI:10.1111/wrr.13100].