Basic Information
Symbol
hsa-miR-1538
RNA class
miRNA
mature miRNA
Alias
hsa-miR-1538
MIR1538
MicroRNA 1538
Location (GRCh38)
-
Forensic tag(s)
Chronological age estimation
External database
Sequence & Structure
Secondary Structure
Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-42.00 kcal/mol
Thermodynamic ensemble
Free energy:
-42.85 kcal/mol
Frequency:
0.4193
Diversity:
4.80
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context
A review of human studies indicates the miR-1538 is an age-related miRNA, with its expression significantly reduced in peripheral blood mononuclear cells from older individuals [Silva et al. DOI:10.1016/J.Fsigen.2014.09.002]. Further research in humans confirms the miR-1538 is significantly reduced in older adults, supporting its role as a biomarker for age estimation [Song et al. DOI:10.1007/s00414-023-03091-1].