Basic Information

Symbol
hsa-mir-154
RNA class
miRNA miRNA hairpin
Alias
MIR154 MicroRNA 154 Hsa-MiR-154-5p Hsa-MiR-154-3p Hsa-Mir-154 MIRN154 Hsa-Mir-154-P1_pre MIMAT0000452 MIMAT0000453 MI0000480 Mir-154
Location (GRCh38)
19:53754018-53754102
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Wound age identification Forensic psychiatry evaluation
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-154
Sequence length
84 nt
GC content
0.4048

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-37.50 kcal/mol
Thermodynamic ensemble
Free energy: -38.81 kcal/mol
Frequency: 0.1203
Diversity: 9.15
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context

A study in mice demonstrated that the mir-154 is upregulated in brain tissue biopsy at 24 hours and 7 days following mild traumatic brain injury, identifying it as a potential biomarker [Martinez & Peplow DOI:10.4103/1673-5374.219025]. In human postmortem brain studies, the mir-154 was found to be downregulated in the prefrontal cortex of subjects with both schizophrenia and bipolar disorder [Yoshino & Dwivedi DOI:10.3389/fpsyt.2020.543893].